Check this out: Direct Note Access.
Watch the video and see how they're messing around with guitar chords via the note editor. What's interesting about this to me is that it seems like software is getting to the point where it might start bringing out the most in acoustic instruments. I'm not much of a geardhead by any means, but I remember when doing "amp modeling" on GuitarRig was a big deal. And now this!
Related to this: in the brief interview between Paul Frick and Littlewhiteearbuds on the latest podcast, Frick mentions doing an organic/acoustic group with the duo Scott. A new record by the duo House on House features what sounds a lot like a standup piano (doubt those are samples). Is it possible that software is going to become more and more "transparent" over time, aiding the use of real instruments rather than being the instrument itself?
Somewhat related (refutation):
Moritz Von Oswald, Max Louderbauer, and Vladislav Delay @ Club Transmediale, 2008.
8 hours ago